Atorvastatin and hormone therapy effects on APOE mRNA expression in hypercholesterolemic postmenopausal women

Statins have additive effects to vertebral bone mineral density in combination with risedronate in hypercholesterolemic postmenopausal women.

BACKGROUND Recent data suggest that statins used in the treatment of hypercholesterolaemia decrease fracture risk. In this study, we aimed to investigate prospectively whether statins have an additive effect to bisphosphonates (risedronate) according to the primary hypothesis that the addition of atorvastatin to risedronate would produce an increase, from baseline, in lumbar vertebrae and total...

The effects of aerobic training before and after the induction of Alzheimer’s disease on ABCA1 and APOE mRNA expression and the level of soluble Aβ1-42 in the hippocampus of male Wistar rats

Objective(s): The purpose of this study was to investigate the effects of aerobic training before and after the induction of Alzheimer’s disease on ABCA1 and APOE mRNA expression and the level of soluble Aβ1-42 in the hippocampus of male Wistar rats.Materials and Methods: Ninety six eight-week-old male Wistar rats were randomly divided into two groups: Training (n=48) and Rest (n=48). After fou...

Aortic debris and coronary guiding catheters.

1. Sbarouni E, Kyriakides ZS, Kremastinos D. The effect of hormone replacement therapy alone and in combination with simvastatin on plasma lipid levels of hypercholesterolemic postmenopausal women with coronary artery disease. J Am Coll Cardiol 1998;32:1244 –50. 2. Fak AS, Erenus M, Tezcan H, Caymaz O, Atagündüz P, Tokay S, Toprak A, Oktay Ş, Oktay A. Effects of simvastatin alone and in combina...

Additive effects of simvastatin and hormone replacement therapy in hypercholesterolemic postmenopausal women.

Anti-Inflammatory Effects of Atorvastatin by the Modulation of NF-κB Expression during Hyperglycemia-Induced Nephropathy in Rat

Objective: Atorvastatin has the pleiotropic effects, including anti-inflammation and antioxidant. Therefore, this study considered to examine the effects of atorvastatin on NF-қB expression, as a main transcription factor for expression of inflammatory cytokines, in hyperglycemia-induced nephropathy in rat. Materials and Methods: Twenty four male Wistar rats were randomly divided into four g...